BioMaths Colloquium Series - 2016/17
02 March 2017 - 3pm Maths Seminar Room
(room 224 Talbot Building 2nd floor)
Towards a 3D distribution model of drugs in the brain
On the way towards a 3D spatial drug distribution model of the brain, we first developed a 2D model that gives more detailed insight into the change of drug concentration in the brain in both time and space. The model consists of a system of a partial differential equation and ordinary differential equations that describe the concentration of free drug in the brain and the concentrations of free and bound receptors on the surface of the brain cells. In this model we integrate both the drug distribution and target interaction kinetics, to ultimately improve the prediction of drug action in the brain.
The discussions will continue over biscuits and tea/coffee after the seminar.
Hope to see many of you!